Baobab Leaf

Baobab leaf is a great source of protein, vitamins A and  C, polyphenols, terpenes, Vitamin B1, B2, Beta-carotene, and minerals iron, zinc, and calcium. Baobab leaves are traditionally used as food and medicine. They can be eaten fresh and also dried to make a green powder used in flavour drinks and sauces. Recent research shows that Baobab Leaves can help with blood sugar regulation and immune enhancement and reduce skin pigmentation.

APPLICATION.

  • Herbal tea, drinks, syrups, sauces
  • Low glycemic formulations
  • Tinctures
  • Cosmetic masks and creams

HEALTH BENEFITS

Low glycemic

Baobab leaf extract is rich in saponins, mucilage content, and polyphenols that inhibit enzymes amylase, glucosidase, and aldose reductase, producing a hypoglycemic effect.

Hypolipidemic 

Research into the effect of alcohol extract of Baobab leaf on blood lipids showed a significant decrease in total cholesterol while enhancing the HDL level. It was also reported that the administration of Adansonia digitata extract reduces Triglycerides and LDL in diabetic rats.

Antioxidant Activity

Elevated oxidative stress in diabetic patients involves extensive lipid peroxidation. It is reported that Baobab leaf extract is rich in flavonoids and phenolic compounds that reduce free radical activity observed in patients with diabetes.

Anti-inflammatory

An alcohol extract of Adansonia digitata leaf inhibits lipopolysaccharide-induced iNOS expression and inhibits NF-kB important targets to reduce inflammation associated with many chronic, life-threatening diseases.

Antiviral

Baobab Leaf extract has antiviral activity similar to Echinacea extract.

Analgesic

Research into analgesic testing revealed that Baobab leaf extracts possess remarkable anti-nociceptive effects. Neuropathic pain relief was linked to its flavonoid and mineral content. These substances alleviate neuropathic pain by various mechanisms, including the inhibition of NF-κB to suppress inflammation and the up-regulation of Nrf2 to improve oxidative defense.

CERTIFICATIONS

  • GMP-certified processing facility
  • USDA Organic, EU Organic, Canadian Organic
  • OU Kosher
  • Certified B- Corporation

RESEARCH

Low Glycemic

Dimopoulou M, Alba K, Sims IM, Kontogiorgos V. Structure and rheology of pectic polysaccharides from baobab fruit and leaves. Carbohydr Polym. 2021 Dec 1;273:118540. doi: 10.1016/j.carbpol.2021.118540. Epub 2021 Aug 8. PMID: 34560952.

Di Lucchio LM, Fensholt R, Markussen B, Ræbild A. Leaf phenology of thirteen African origins of baobab (Adansonia digitata (L.)) as influenced by daylength and water availability. Ecol Evol. 2018 Oct 26;8(22):11261-11272. doi: 10.1002/ece3.4600. PMID: 30519442; PMCID: PMC6262930.

Tsetegho Sokeng AJ, Sobolev AP, Di Lorenzo A, Xiao J, Mannina L, Capitani D, Daglia M. Metabolite characterization of powdered fruits and leaves from Adansonia digitata L. (baobab): A multi-methodological approach. Food Chem. 2019 Jan 30;272:93-108. doi: 10.1016/j.foodchem.2018.08.030. Epub 2018 Aug 9. PMID: 30309609.

Cicolari S, Dacrema M, Tsetegho Sokeng AJ, Xiao J, Atchan Nwakiban AP, Di Giovanni C, Santarcangelo C, Magni P, Daglia M. Hydromethanolic Extracts from Adansonia digitata L. Edible Parts Positively Modulate Pathophysiological Mechanisms Related to the Metabolic Syndrome. Molecules. 2020 Jun 21;25(12):2858. doi: 10.3390/molecules25122858. PMID: 32575811; PMCID: PMC7356617.

Ebaid H, Bashandy SAE, Alhazza IM, Hassan I, Al-Tamimi J. Efficacy of a Methanolic Extract of Adansonia digitata Leaf in Alleviating Hyperglycemia, Hyperlipidemia, and Oxidative Stress of Diabetic Rats. Biomed Res Int. 2019 Mar 7;2019:2835152. doi: 10.1155/2019/2835152. PMID: 30984778; PMCID: PMC6431509.

Zeitoun H, Michael-Jubeli R, El Khoury R, Baillet-Guffroy A, Tfayli A, Salameh D, Lteif R. Skin lightening effect of natural extracts coming from Senegal botanical biodiversity. Int J Dermatol. 2020 Feb;59(2):178-183. doi: 10.1111/ijd.14699. Epub 2019 Nov 4. PMID: 31681985.

BUSSON F, DENIEL P, TOURY J. Composition en acides aminés des feuilles et de la pulpe de fruit du baobab (Adansonia digitata Linn) [Amino acid composition of the leaves and fruit pulp of baobab (Adansonia digitata Linn.)]. Bull Soc Chim Biol (Paris). 1958 Jun 9;40(4):711-4. French. PMID: 13546894.

Irondi EA, Akintunde JK, Agboola SO, Boligon AA, Athayde ML. Blanching influences the phenolic composition, antioxidant activity, and inhibitory effect of Adansonia digitata leaves extract on α-amylase, α-glucosidase, and aldose reductase. Food Sci Nutr. 2016 May 25;5(2):233-242. doi: 10.1002/fsn3.386. PMID: 28265358; PMCID: PMC5332274.

Baky MH, Badawy MT, Bakr AF, Hegazi NM, Abdellatif A, Farag MA. Metabolome-based profiling of African baobab fruit (Adansonia digitata L.) using a multiplex approach of MS and NMR techniques about its biological activity. RSC Adv. 2021 Dec 13;11(63):39680-39695. doi: 10.1039/d1ra08277a. PMID: 35494142; PMCID: PMC9044842

Antiviral

Selvarani, V. and Hudson James, B., 2009. Multiple inflammatory and antiviral activities in Adansonia digitata (Baobab) leaves, fruits and seeds. J Med Plants Res, 3(8), pp.576-582.

Skin clarifying

Zeitoun H, Michael-Jubeli R, El Khoury R, Baillet-Guffroy A, Tfayli A, Salameh D, Lteif R. Skin lightening effect of natural extracts coming from Senegal botanical biodiversity. Int J Dermatol. 2020 Feb;59(2):178-183. doi: 10.1111/ijd.14699. Epub 2019 Nov 4. PMID: 31681985.

Detoxifying

Adegoke AM, Gbadegesin MA, Odunola OA. Methanol Extract of Adansonia digitata Leaf Protects Against Sodium Arsenite-induced Toxicities in Male Wistar Rats. Pharmacognosy Res. 2017 Jan-Mar;9(1):7-11. doi: 10.4103/0974-8490.199768. PMID: 28250647; PMCID: PMC5330107.
Atuadu V, Benneth BA, Oyem J, Esom E, Mba C, Nebo K, Ezemeka G, Anibeze C. Adansonia digitata L. leaf extract attenuates lead-induced cortical histoarchitectural changes and oxidative stress in the prefrontal cortex of adult male Wistar rats. Drug Metab Pers Ther. 2020 Oct 21:/j/dmdi.ahead-of-print/dmdi-2020-0116/dmdi-2020-0116.xml. doi: 10.1515/dmdi-2020-0116. Epub ahead of print. PMID: 33085634.

Anti-inflammatory

Ayele Y, Kim JA, Park E, Kim YJ, Retta N, Dessie G, Rhee SK, Koh K, Nam KW, Kim HS. A Methanol Extract of Adansonia digitata L. Leaves Inhibits Pro-Inflammatory iNOS Possibly via the Inhibition of NF-κB Activation. Biomol Ther (Seoul). 2013 Mar;21(2):146-52. doi: 10.4062/biomolther.2012.098. PMID: 24009873; PMCID: PMC3762316.

Analgesic

Mumtaz T, Rizwani GH, Shareef H. Analgesic activities of crude ethanolic extract and various fractions of Adansonia digitata L. grown at the sindh province of Pakistan. Pak J Pharm Sci. 2017 Sep 30(5):1657-1663. 

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